The adaptive immune response is non-specific

AUMC Immunology Questions

Immunology Quiz-1 Each answer is equal 0.1 points (5 points – maximum)

True or false?

 1) The adaptive immune response is non-specific

2) The adaptive defense must first be primed by exposure to an antigen

3) Humoral immunity is mediated by cells

4) Immunological memory – protection against the recurring infection

5) In vivo stem cells are rapidly dividing

 6) Neutrophils are granulocytes

7) Both basophils and mast cells are responsible for inflammatory and allergic reactions

8) Monocytes migrate from the blood stream into tissues and become dendritic cells

9) Dendritic cells process and present foreign molecules as antigens to T-lymphocytes

10) Plasma cells secrete large volumes of antibodies

11) Lymphocytes belong to granulocytes

12) IgM are widely used in molecular and cell biology as well as in clinical lab applications

13) Signal transduction means that the original signaling molecule is not physically passed along a signaling pathway

14) Autocrine signals target cells in the vicinity of the emitting cell

15) Antigens are signaling molecules for immune cells

16) Complement enhances inflammation

 17) Complement is the main factor in the membrane attack complex

18) The resulting from complement activation smaller polypeptide fragments induce and promote inflammation

19) Properdin enhances complement activation

20) Lysozyme is present in lymphocytes

21) Lysozyme is thermally stable at the temperature up to 72 ? and at pH 5.0

22) Lysozyme plays an important role in immunology of infants

23) Opsonization – coating the phagocytes with proteins that facilitate phagocytosis

24) Macrophages are monocytes that move from the blood to tissues

25) M2 macrophages induce inflammation

26) Dendritic cells are present in those tissues that are in contact with the external environment

27) Dendritic cells process antigens and present them on the cell surface to the T cells

28) Neutrophils act mainly on viruses and parasites

29) Neutrophils are first responders to the sites of inflammation

30) Myeloperoxidase is an enzyme that is most abundantly present in the granules of neutrophils

31) Natural antibodies are important in preventing autoimmunity

32) Anti-microbial peptides (cationic and anionic proteins) exemplify the microbiological barrier

33) Antimicrobial peptides may act as immunomodulators

34) Myeloperoxidase enhances inflammation and apoptosis

35) Inflammation is a protective response involving immune cells, blood vessels, and molecular mediators

36) One of the functions of inflammation is to initiate tissue repair

37) Interleukins are cytokines that are produced and act on cells within all tissues 1

38) Macrophages secrete cytokines that attract other immune cells to the sites of inflammation

39) IL-8 is one of the inflammatory cytokines that are secreted by macrophages

40) IL-12 recruit NK cells

41) Toll-like receptors directly participate in phagocytosis

 42) Toll-like receptors are expressed only on macrophages

 43) NFkappaB is one of the most important genes that are activated by TLRs

44) Interferons can be released only by immune cells

45) Interferons may also be released in response to bacteria, parasites and tumor cells

46) IFN-α and IFN-β act mainly against viral infections

47) IFN-γ is critical for both innate and adaptive immunity

48) IFN-γ is an important activator of macrophages

49) NK do not require activation to kill their target cells

50) NK cells uniquely express CD3 marker 2