MPH501 Module 6 Quiz Latest 2020 January

Question

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MPH501 Quantitative Methods for Public Health Application

Module 6 Quiz

Question 1Some scientists believe that alcoholism is linked to social isolation.  One measure of social isolation is marital status.  A study of 280 adults is conducted and each participant is classified as not alcoholic, diagnosed alcoholic or undiagnosed alcoholic, and categorized by marital status.  Is there significant evidence of an association?  Run the appropriate test at a 5% level of significance.

Diagnosed
Alcoholic

Undiagnosed
Alcoholic

Not Alcoholic

 

Married

21

37

58

Not Married

59

63

42

Question 2Suppose a hypertension trial is mounted and 18 participants are randomly assigned to one of the comparison treatments.  Each participant takes the assigned medication and their systolic blood pressure (SBP) is recorded after 6 months on the assigned treatment.  The data are as follows.

Standard Treatment

Placebo

New Treatment

124

134

114

111

143

117

133

148

121

125

142

124

128

150

122

115

160

128

Is there a difference in mean SBP among treatments?  Run the appropriate test at []=0.05. 

Question 3A clinical trial is conducted to compare an experimental medication to placebo to reduce the symptoms of asthma.  Two hundred participants are enrolled in the study and randomized to receive either the experimental medication or placebo.  The primary outcome is self-reported reduction of symptoms.  The data are recorded as follows.

Change in Symptoms

 

Treatment

Much Worse

Worse

No change

Better

Much Better

Experimental

10

17

35

28

10

Placebo

12

25

42

12

9

 

Is there a difference in change in symptoms by treatment group?  Run the appropriate test at a 5% level of significance.

Question 4The following data was collected in a clinical trial evaluating a new medication designed to improve wound healing in trauma patients.  The new compound is compared against a placebo.  After treatment for 10 days with the new compound or placebo the extent of wound healing is measured and the data are shown below.

Percent Wound Healing

 

Treatment

0-25%

26-50%

51-75%

76-100%

New psoriasis medication (n=125)

15

37

32

41

Placebo (n=125)

36

45

34

10

 

Is there a difference in the extent of wound healing by treatment?  (Hint:  Are treatment and the percent wound healing independent?)  Run the appropriate test at a 5% level of significance.

 

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